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On May 20, a team led by Professor Bichun Li and Professor Guohong Chen from the College of Animal Science and Technology at Yangzhou University published online an article in Nature Communications titled "Production of viable chicken by allogeneic transplantation of primordial germ cells induced from somatic cells". The allogeneic transplantation of primordial germ cells (PGCs) derived from somatic cells overcomes the limitation of avian cloning. Here, they transdifferentiate chicken embryo fibroblasts (CEFs) from black feathered Langshan chickens to PGCs and transplant them into White P...
On May 20, 2021, the team led by Professor Zhiqiang Wang from the College of Veterinary Medicine at Yangzhou University published their findings titled “Gut microbiome alterations in high-fat-diet-fed mice are associated with antibiotic tolerance” in Nature Microbiology. Antibiotic tolerance, the ability of a typically susceptible microorganism to survive extended periods of exposure to antibiotics, has a critical role in chronic and recurrent bacterial infections, and facilitates the evolution of antibiotic resistance. However, the physiological factors that contribute to the development of...
On January 7th, Jiangsu Provincial People’s Government announced the winners of the 2020 Jiangsu Provincial Science and Technology Award. Seven projects of Yangzhou University won the awards, including two first prizes, one second prize and four third prizes. Professor Chen Guohong at College of Animal Science & Technology was awarded the first prize for the research project of "Evaluation of chicken genetic resources, germplasm innovation and industrial application". The project of "Key technology and application of permeable storage and water purification pavement" led by Professor Kan...
Despite the growing resistance, tetracycline antibiotics remain among the most widely used antibiotics in clinic and agricultural settings. Indeed, tetracyclines ranked in one of the top three antibiotics of the clinical prescriptions in the United States in 2010. Furthermore, other derivatives including doxycycline, minocycline and tigecycline were continuously introduced into clinical practices. These tetracyclines have the broad‐spectrum activity against both Gram‐positive and Gram‐negative bacteria. Compared to other antibiotics, tetracyclines such as doxycycline and minocycline have be...
A team from the College of Bioscience and Biotechnology at Yangzhou University published their findings in Angewandte Chemie International Edition (IF+12.3) where they report an engineered enzyme that can monooxygenate unprotected tryptophan into the corresponding 3a‐hydroxyhexahydropyrrolo[2,3‐b]indole‐2‐carboxylic acid (HPIC) in a single, scalable step with excellent turnover number and diastereoselectivity. Taking advantage of directed evolution, they analyzed the stepwise oxygen‐insertion mechanism of tryptophan 2,3‐dioxygenases, and transformed tryptophan 2,3‐dioxygenase from Xanth...
In February 2020, the researchers from YZU published a review article in Cellular and Molecular Life Sciences where they revisited and described the roles of various subsets of immune cells in host defense against MDV infection and proposed areas of research that need to be further explored.Marek’s disease virus (MDV) is a highly oncogenic alphaherpesvirus that causes deadly T-cell lymphomas and serves as a natural virus-induced tumor model in chickens. Although Marek’s disease (MD) is well controlled by current vaccines, the evolution of MDV field viruses towards increasing virulence is con...
Despite their early experimental production and observation, the unambiguous molecular structures of metal-containing boron nitride (BN) nanocages still remain mysterious. It has been commonly assumed that this family of compounds has the metal atom confined inside the cage, just like their isoelectronic cousins, carbon metallofullerenes do. Here, we demonstrate that Ti(BN)n (nn = 12–24) complexes have, unexpectedly, an exohedral structure instead of an endohedral one, which could be verified by collision-induced dissociation experiments. The predicted global minimum structures exhibit some c...
Professor Diao Guowang and Dr. Sun Yan from the College of Chemistry and Chemical Engineering at Yangzhou University have published a pivotal paper in Nature Communications that has uncovered a new line of discovery regarding photocatalytic reaction studies.As reported in their paper, entitled “Stimulus-responsive light-harvesting complexes based on the pillararene-induced co-assembly of b-carotene and chlorophyll,” the investigators concluded that the successful creation of HMS provides sophisticated strategies to generate carotenoids-based hierarchical model, which will result in...
Tel: 86-514-87971858 Fax: 86-514-87311374 Add: 88 South Daxue Road, Yangzhou, Jiangsu Province
Copyright © 2019 Yangzhou University All Rights Reserved. 苏公网安备 32100302010246号