On October 22, Professor Shi Huoying 's research team from the College of Veterinary Medicine made latest developments in new bacterial delivery vectors and published a paper in Advanced Science with the title of A Bacterial mRNA-Lysis-Mediated Cargo Release Vaccine System for Regulated Cytosolic Surveillance and Optimized Antigen Delivery.

Professor Shi Huoying 's research team developed a new Salmonella vector delivery system, called Salmonella mRNA interference enzyme system ( SIRV-system ) based on RDAS-system, RDA-system and TA-system. In this study, streptococcus suis was used as a pathogen evaluation model, and it was found that the SIRV-system vector delivering protective antigens showed excellent immunogenicity and protection in mouse and pig models. The above findings indicate that SIRV-system can be regarded as a potential new prevention or treatment vector for efficient delivery of exogenous protein drugs or in vivo antigens.