On October 6, the team led by Professor Wang Zhiqiang from the College of Veterinary Medicine published a paper entitled A Dietary Source of High Level of Fluoroquinolone Tolerance in mcr-Carrying Gram-negative Bacteria in the TOP journal Research, which is co-founded by the China Association for Science and Technology and the American Association for the Advancement of Science. Studies have found that the food additive potassium sorbate can induce high levels of fluoroquinolone resistance in bacteria carrying mcr. While exogenous supplementation of succinic acid can reverse this situation, providing a scientific basis for understanding and solving the problem of antibiotic resistance.

This study reported a new food-borne factor-induced antibiotic tolerance. It reveals the potential risk of colistin-resistant and fluoroquinolone-resistant bacteria induced by potassium sorbate in a complex clinical environment, and provides a new insight for the formation and control of antibiotic tolerance.

Further information can be found at: https://syxy.yzu.edu.cn/info/1076/10591.htm